No, I’m not a doctor. But I am a 68-year-old male with Type II diabetes who has been previously directed to take a low-dose aspirin every day. Thus, these results reported in the most recent issue of The New England Journal of Medicine are of some interest:
- Aspirin use prevented serious vascular events in persons who had diabetes and no evident cardiovascular disease at trial entry, but it also caused major bleeding events. The absolute benefits were largely counterbalanced by the bleeding hazard. Here.
- Higher all-cause mortality was observed among apparently healthy older adults who received daily aspirin than among those who received placebo and was attributed primarily to cancer-related death. In the context of previous studies, this result was unexpected and should be interpreted with caution. Here.
- The use of low-dose aspirin as a primary prevention strategy in older adults resulted in a significantly higher risk of major hemorrhage and did not result in a significantly lower risk of cardiovascular disease than placebo. Here.
- Aspirin use in healthy elderly persons did not prolong disability-free survival over a period of 5 years but led to a higher rate of major hemorrhage than placebo. Here.
I’m seeing both my cardiologist and my endocrinologist this week. I’ll wait to see what they say.